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Population geneticists and genealogists collected DNA samples from 196 Irish people, each of whom had four generations of ancestry originating from a common geographical area of the island ie all four grandparents were born within around 30km of one another.
Analyses of the DNA, and comparison with thousands of further samples from Britain and Europe, have revealed geographic clusters within Ireland: so far seven of ‘Gaelic’ Irish ancestry, and three of shared British-Irish ancestry.
These findings add to the knowledge base required to improve the diagnosis of diseases where genes play a strong role, particularly for populations of Irish ancestry.
For more information, see the RCSI's press release, or go straight to the paper published in Scientific Report.